Yazar "Majid, Arshad" için listeleme
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Adipose-derived mesenchymal stem cells reduce autophagy in stroke mice by extracellular vesicle transfer of miR-25
Kuang, Yaoyun; Zheng, Xuan; Zhang, Lin; Ai, Xiaoyu; Venkataramani, Vivek; Kılıç, Ertuğrul; Hermann, Dirk M.; Majid, Arshad; Baehr, Mathias; Doeppner, Thorsten R. (Taylor & Francis Ltd, 2020)Grafted mesenchymal stem cells (MSCs) yield neuroprotection in preclinical stroke models by secreting extracellular vesicles (EVs). The neuroprotective cargo of EVs, however, has not yet been identified. To investigate ... -
Carnosine protects against cerebral ischemic injury by inhibiting matrix-metalloproteinases
Kim, Eun-Hye; Kim, Eun-Sun; Shin, Donggeun; Kim, Donghyun; Choi, Sungbin; Shin, Young-Jun; Kim, Kyeong-A; Noh, Dabi; Çağlayan, Ahmet Burak; Rajanikant, G. K.; Majid, Arshad; Bae, Ok-Nam (MDPI, 2021)Stroke is one of the leading causes of death and disability worldwide. However, treatment options for ischemic stroke remain limited. Matrix-metalloproteinases (MMPs) contribute to brain damage during ischemic strokes by ... -
Ischemic post-conditioning induces post-stroke neuroprotection via Hsp70-mediated proteasome inhibition and facilitates neural progenitor cell transplantation
Doeppner, Thorsten R.; Doehring, Maria; Kaltwasser, Britta; Majid, Arshad; Lin, Fengyan; Bahr, Mathias; Kılıç, Ertuğrul; Hermann, Dirk M. (Humana Press Inc, 2017)In view of the failure of pharmacological therapies, alternative strategies promoting post-stroke brain repair are needed. Post-conditioning is a potentially promising therapeutic strategy, which induces acute neuroprotection ... -
Neural progenitor cell-derived extracellular vesicles enhance blood-brain barrier integrity by NF-kappa B (Nuclear Factor-kappa B)-dependent regulation of ABCB1 (ATP-Binding Cassette Transporter B1) in stroke mice
Zhang, Lin; Graf, Irina; Kuang, Yaoyun; Zheng, Xuan; Haupt, Matteo; Majid, Arshad; Kılıç, Ertuğrul; Hermann, Dirk M.; Psychogios, Marios-Nikos; Weber, Martin S.; Ochs, Jasmin; Baehr, Mathias; Doeppner, Thorsten R. (Lippincott Williams & Wilkins, 2021)Objective: Extracellular vesicles (EVs) derived from neural progenitor cells enhance poststroke neurological recovery, albeit the underlying mechanisms remain elusive. Since previous research described an enhanced poststroke ... -
Neuroprotective potential of carnosine in cerebrovascular diseases
Neelakandan, A. R.; Bae, Ok-Nam; Majid, Arshad; Çağlayan, Ahmet Burak; Rajanikant, G. K. (Springer, 2022)The growing prevalence, the risk of disabilities, and the lack of effective causal or disease-modifying therapies make cerebrovascular disorders a serious burden. Carnosine, an evolutionarily conserved endogenous dipeptide ...